Urolithin B suppressed osteoclast activation and reduced bone loss of osteoporosis via inhibiting <scp>ERK</scp>/<scp>NF‐κB</scp> pathway

Li, Yajun; Zhuang, Qi; Tao, Lihong; Zheng, Kai; Chen, Shuangshuang; Yang, Yunshang; Feng, Chengcheng; Wang, Zhifang; Shi, Haiwei; Shi, Jiandong; Fang, Yiling; Xiao, Long; Geng, Dechun; Wang, Zhirong

doi:10.1111/cpr.13291

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Urolithin B suppressed osteoclast activation and reduced bone loss of osteoporosis via inhibiting ERK/NF‐κB pathway

Shared by NobleBlocks on Jun 16, 2022 • 12:00 AM UTC

Authors:

Yajun Li

Qi Zhuang

Lihong Tao

Abstract

Abstract Objectives The main target of current drugs for alleviating bone loss is osteoclasts. However, the long‐term application of such drugs will also cause side effects. Therefore, it is of great need to develop new and safer therapeutics for osteoporosis. In recent years, drug development based...

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