Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit

Lamontagne, François; Masse, Marie-Hélène; Ménard, Julie; Sprague, Sheila; Pinto, Ruxandra; K. Heyland, Daren; J Cook, Deborah; Battista, Marie‐Claude; G. Day, Andrew; Guyatt, Gordon; Kanji, Salmaan; Parke, Rachael; McGuinness, Shay; Tirupakuzhi Vijayaraghavan, Bharath-Kumar; Annane, Djillali; Cohen, Dian; M. Arabi, Yaseen; Bolduc, Brigitte; Marinoff, Nicole; Rochwerg, Bram; Millen, Tina; O. Meade, Maureen; Hand, Lori; Watpool, Irene; Porteous, Rebecca; J. Young, Paul; D’Aragon, Frédérick; P. Belley‐Côté, Emilie; Carbonneau, Élaine; Clarke, France; M. Maslove, David; Hunt, Miranda; Chassé, Michaël; Lebrasseur, Martine; Lauzier, François; Mehta, Sangeeta; Quiroz-Martinez, Hector; Rewa, Oleksa; Charbonney, Emmanuel; Seely, Andrew; J. Kutsogiannis, Demetrios; Leblanc, Rémi; Mekontso Dessap, Armand; Mele, Tina; F. Turgeon, Alexis; Wood, Gordon; S. Kohli, Sandeep; Shahin, Jason; Twardowski, Paweł; K. J. Adhikari, Neill

doi:10.1056/nejmoa2200644

Public

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit

Published in New England Journal of Medicine • Jun 15, 2022

Authors:

François Lamontagne

Marie-Hélène Masse

Julie Ménard

Abstract

BACKGROUND: Studies that have evaluated the use of intravenous vitamin C in adults with sepsis who were receiving vasopressor therapy in the intensive care unit (ICU) have shown mixed results with respect to the risk of death and organ dysfunction. METHODS: In this randomized, placebo-controlled tri...

Subject

Intensive care unit

Sepsis

Medicine

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