Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus

Isidro, Joana; Borges, Vítor; Pinto, Miguel; Sobral, Daniel; Dourado Santos, João; Nunes, Alexandra; Mixão, Verónica; Ferreira, Rita; Santos, Daniela; Duarte, Silvia; Vieira, Luís; José Borrego, Maria; Núncio, Sofia; Lopes de Carvalho, Isabel; Pelerito, Ana; Cordeiro, Rita; Paulo Gomes, João

doi:10.1038/s41591-022-01907-y

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Phylogenomic characterization and signs of microevolution in the 2022 multi-country outbreak of monkeypox virus

Shared by NobleBlocks on Jun 24, 2022 • 12:00 AM UTC

Authors:

Joana Isidro

Vítor Borges

Miguel Pinto

Abstract

Abstract The largest monkeypox virus (MPXV) outbreak described so far in non-endemic countries was identified in May 2022 (refs. 1–6 ). In this study, shotgun metagenomics allowed the rapid reconstruction and phylogenomic characterization of the first MPXV outbreak genome sequences, showing that thi...

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