The<scp>PI3K</scp>/<scp>AKT</scp>signalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities

He, Xuegang; Li, Ying; Deng, Bo; Lin, Aixin; Zhang, Guangzhi; Ma, Miao; Wang, Yonggang; Yang, Yong; Kang, Xuewen

doi:10.1111/cpr.13275

Public

ThePI3K/AKTsignalling pathway in inflammation, cell death and glial scar formation after traumatic spinal cord injury: Mechanisms and therapeutic opportunities

Shared by NobleBlocks on Jun 26, 2022 • 12:00 AM UTC

Authors:

Xuegang He

Ying Li

Bo Deng

Abstract

Abstract Objects Traumatic spinal cord injury (TSCI) causes neurological dysfunction below the injured segment of the spinal cord, which significantly impacts the quality of life in affected patients. The phosphoinositide 3kinase/serine‐threonine kinase (PI3K/AKT) signaling pathway offers a potentia...

Discussions