Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?

Kou, Meng; Huang, Li; Yang, Jinjuan; Chiang, Zhixin; Chen, Shaoxiang; Liu, Jie; Guo, Liyan; Zhang, Xiaoxian; Zhou, Xiaoya; Xu, Xiang; Yan, Xiaomei; Wang, Yan; Zhang, Jinqiu; Xu, Aimin; Tse, Hung‐Fat; Lian, Qizhou

doi:10.1038/s41419-022-05034-x

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Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?

Published in Cell Death and Disease • Jul 4, 2022

Authors:

Meng Kou

Li Huang

Jinjuan Yang

Abstract

Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and multipotent differentiation. There is compelling evidence that the therapeutic effect of MSCs mainly depends on their paracrine...

Subject

Mesenchymal stem cell

Paracrine signalling

Cell biology

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