Neutrophil extracellular traps mediate m<sup>6</sup>A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells

Zhang, Hao; Liu, Jinlong; Zhou, Yilu; Qu, Mengdi; Wang, Yanghanzhao; Guo, Kefang; Shen, Ruling; Sun, Zhirong; P. Cata, Juan; Yang, Shuofei; Chen, Wankun; Miao, Changhong

doi:10.7150/ijbs.69141

Public

Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells

Published in International Journal of Biological Sciences • Jan 1, 2022

Authors:

Hao Zhang

Jinlong Liu

Yilu Zhou

Abstract

, we elucidated and confirmed the critical role of ferroptosis in NETs-induced ALI. These findings support a role for NETs-induced METTL3 modification and the subsequent induction of ferroptosis in the pathogenesis of sepsis-associated ALI.

Subject

Neutrophil extracellular traps

Sepsis

Pathogenesis

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!