Exploration of DNA processing features unravels novel properties of ICE conjugation in Gram-positive bacteria

Laroussi, Haifa; Aoudache, Yanis; Robert, Emilie; Libante, Virginie; Thiriet, Louise; Mias‐Lucquin, Dominique; Douzi, Badreddine; Roussel, Yvonne; Chauvot de Beauchêne, Isaure; Soler, Nicolás; Leblond‐Bourget, Nathalie

doi:10.1093/nar/gkac607

Public

Exploration of DNA processing features unravels novel properties of ICE conjugation in Gram-positive bacteria

Published in Nucleic Acids Research • Jul 18, 2022

Authors:

Haifa Laroussi

Yanis Aoudache

Emilie Robert

Abstract

Integrative and conjugative elements (ICEs) are important drivers of horizontal gene transfer in prokaryotes. They are responsible for antimicrobial resistance spread, a major current health concern. ICEs are initially processed by relaxases that recognize the binding site of oriT sequence and nick ...

Subject

Biology

DNA

Bacterial conjugation

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