Plasma Aβ42/40 ratio, p‐tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross‐sectional and longitudinal study in the AIBL cohort

Chatterjee, Pratishtha; Pedrini, Steve; D. Doecke, James; N. Thota, Rohith; L. Villemagne, Victor; Doré, Vincent; Kumar Singh, Abhay; Wang, Penghao; R. Rainey‐Smith, Stephanie; Fowler, Christopher; Taddei, Kevin; R. Sohrabi, Hamid; P. Molloy, Mark; Ames, David; Maruff, Paul; C. Rowe, Christopher; L. Masters, Colin; N. Martins, Ralph

doi:10.1002/alz.12724

Public

Plasma Aβ42/40 ratio, p‐tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross‐sectional and longitudinal study in the AIBL cohort

Published in Alzheimer s & Dementia • Jul 21, 2022

Authors:

Pratishtha Chatterjee

Steve Pedrini

James D. Doecke

Abstract

INTRODUCTION: Plasma amyloid beta (Aβ)1-42/Aβ1-40 ratio, phosphorylated-tau181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) are putative blood biomarkers for Alzheimer's disease (AD). However, head-to-head cross-sectional and longitudinal comparisons of the afore...

Subject

Biomarker

Cohort

Apolipoprotein E

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