Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases

Mathieu, Vanhove,; Adam C., Rechtless,; Anne, Sicard,; Adrien, Rieux,; Helvecio D., Coletta-Filho,; De La Fuente, Leonardo; C. Stenger, Drake; P. P. Almeida, Rodrigo

doi:10.1128/aem

Public

Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases

Published in Institutional Repository of the University of Granada (University of Granada) • Jan 1, 2018

Authors:

Vanhove, Mathieu

Rechtless, Adam C.

Sicard, Anne

Abstract

ABSTRACT Ancestral sequence reconstruction and resurrection provides useful information \nfor protein engineering, yet its alliance with directed evolution has been \nlittle explored. In this study, we have resurrected several ancestral nodes of fungal \nlaccases dating back 500 to 250 million years...

Subject

Xylella fastidiosa

Subspecies

Recombination

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