Specific anti‐glioma targeted‐delivery strategy of engineered small extracellular vesicles dual‐functionalised by Angiopep‐2 and TAT peptides

Zhu, Zhanchi; Zhai, Yuanxin; Hao, Ying; Wang, Quanwei; Han, Fang; Zheng, Wenlong; Hong, Jing; Cui, Leisha; Jin, Wei; Ma, Sancheng; Yang, Lingyan; Cheng, Guosheng

doi:10.1002/jev2.12255

Public

Specific anti‐glioma targeted‐delivery strategy of engineered small extracellular vesicles dual‐functionalised by Angiopep‐2 and TAT peptides

Published in Journal of Extracellular Vesicles • Aug 1, 2022

Authors:

Zhanchi Zhu

Yuanxin Zhai

Ying Hao

Abstract

Glioma is one of the primary malignant brain tumours in adults, with a poor prognosis. Pharmacological reagents targeting glioma are limited to achieve the desired therapeutic effect due to the presence of blood-brain barrier (BBB). Effectively crossing the BBB and specifically targeting to the brai...

Subject

Glioma

Drug delivery

Cancer research

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