Comprehensive genomic profiling of Finnish lung adenocarcinoma cohort reveals high clinical actionability and SMARCA4 altered tumors with variable histology and poor prognosis

Talvitie, Eva‐Maria; Liljeroos, Lassi; Vilhonen, Heikki; Orte, Katri; Leivo, Ilmo; Kallajoki, Markku; Taimen, Pekka

doi:10.1016/j.neo.2022.100832

Public

Comprehensive genomic profiling of Finnish lung adenocarcinoma cohort reveals high clinical actionability and SMARCA4 altered tumors with variable histology and poor prognosis

Published in Neoplasia • Aug 11, 2022

Authors:

Eva‐Maria Talvitie

Lassi Liljeroos

Heikki Vilhonen

Abstract

INTRODUCTION: Lung adenocarcinoma is the most common type of lung cancer and typically carries a high number of mutations. However, the genetic background of the tumors varies according to patients' ethnic background and smoking status. Little data is available on the mutational landscape and the fr...

Subject

SMARCA4

Adenocarcinoma

Medicine

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