Effect of Aspirin vs Enoxaparin on Symptomatic Venous Thromboembolism in Patients Undergoing Hip or Knee Arthroplasty

Study Group, CRISTAL; S. Sidhu, Verinder; Kelly, Thu‐Lan; Pratt, Nicole; E. Graves, Stephen; Buchbinder, Rachelle; Adie, Sam; Cashman, Kara; N. Ackerman, Ilana; Bastiras, Durga; Brighton, Roger; Burns, Alexander; H. Chong, Beng; Clavisi, Ornella; Cripps, Maggie; Dekkers, Mark; de Steiger, Richard; C. Dixon, Michael; Ellis, Andrew; C. Griffith, Elizabeth; Hale, David; Hansen, Amber; Harris, Anthony; Hau, Raphael; Horsley, Mark; James, D; Khorshid, Omar; Kuo, Leonard; L. Lewis, Peter; Lieu, David; Lorimer, Michelle; J. MacDessi, Samuel; McCombe, Peter; McDougall, Catherine; Mulford, Jonathan; Naylor, Justine; S. Page, Richard; Radovanovic, John; Solomon, Michael; Sorial, Rami; Summersell, Peter; Tran, Phong; L. Walter, William; Webb, Steve; Wilson, Chris; Wysocki, David; A. Harris, Ian

doi:10.1001/jama.2022.13416

Public

Effect of Aspirin vs Enoxaparin on Symptomatic Venous Thromboembolism in Patients Undergoing Hip or Knee Arthroplasty

Published in JAMA • Aug 23, 2022

Authors:

CRISTAL Study Group

Verinder S. Sidhu

Thu‐Lan Kelly

Abstract

Importance: There remains a lack of randomized trials investigating aspirin monotherapy for symptomatic venous thromboembolism (VTE) prophylaxis following total hip arthroplasty (THA) or total knee arthroplasty (TKA). Objective: To determine whether aspirin was noninferior to enoxaparin in preventin...

Subject

Medicine

Randomized controlled trial

Pulmonary embolism

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