Microfluidic Manufacturing of Liposomes: Development and Optimization by Design of Experiment and Machine Learning

Rebollo, René; Oyoun, Feras; Corvis, Yohann; M. El‐Hammadi, Mazen; Saubaméa, Bruno; Andrieux, Karine; Mignet, Nathalie; Alhareth, Khair

doi:10.1021/acsami.2c06627

Public

Microfluidic Manufacturing of Liposomes: Development and Optimization by Design of Experiment and Machine Learning

Published in ACS Applied Materials & Interfaces • Aug 24, 2022

Authors:

René Rebollo

Feras Oyoun

Yohann Corvis

Abstract

Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on the market. Microfluidic-based preparation methods stand up as a promising approach with high reproducibility and the ability to scale up. In this study, liposomes composed of DOPC, cholesterol, and DSPE-PEG 200...

Subject

Microfluidics

Micromixer

Materials science

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