Molecular and cellular evolution of the primate dorsolateral prefrontal cortex

Ma, Shaojie; Škarica, Mario; Li, Qian; Xu, Chuan; D. Risgaard, Ryan; T.N. Tebbenkamp, Andrew; Mato-Blanco, Xoel; Kovner, Rothem; Krsnik, Željka; de Martin, Xabier; Luria, Victor; Martí-Pérez, Xavier; Liang, Dan; Karger, Amir; Schmidt, Danielle; Gomez-Sanchez, Zachary; Cai, Qi; T. Gobeske, Kevin; Pochareddy, Sirisha; Debnath, Ashwin; J. Hottman, Cade; Spurrier, Joshua; Teo, Leon; G. Boghdadi, Anthony; Homman‐Ludiye, Jihane; J. Ely, John; W. Daadi, Etienne; Mi, Da; M. Daadi, Marcel; Marín, Óscar; R. Hof, Patrick; Rašin, Mladen‐Roko; A. Bourne, James; C. Sherwood, Chet; Santpere, Gabriel; J. Girgenti, Matthew; M. Strittmatter, Stephen; M. M. Sousa, André; Šestan, Nenad

doi:10.1126/science.abo7257

Public

Molecular and cellular evolution of the primate dorsolateral prefrontal cortex

Published in Science • Aug 25, 2022

Authors:

Shaojie Ma

Mario Škarica

Qian Li

Abstract

The granular dorsolateral prefrontal cortex (dlPFC) is an evolutionary specialization of primates that is centrally involved in cognition. We assessed more than 600,000 single-nucleus transcriptomes from adult human, chimpanzee, macaque, and marmoset dlPFC. Although most cell subtypes defined transc...

Subject

Dorsolateral prefrontal cortex

Macaque

Marmoset

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!