An Enzyme‐Engineered Nonporous Copper(I) Coordination Polymer Nanoplatform for Cuproptosis‐Based Synergistic Cancer Therapy

Xu, Yuzhi; Liu, Si‐Yang; Zeng, Leli; Ma, Hansu; Zhang, Yanfei; Yang, Huihui; Liu, Yuchen; Fang, Shuo; Zhao, Jing; Xu, Yunsheng; R. Ashby, Charles; He, Yulong; Dai, Zong; Pan, Yihang

doi:10.1002/adma.202204733

Public

An Enzyme‐Engineered Nonporous Copper(I) Coordination Polymer Nanoplatform for Cuproptosis‐Based Synergistic Cancer Therapy

Published in Advanced Materials • Sep 2, 2022

Authors:

Yuzhi Xu

Si‐Yang Liu

Leli Zeng

Abstract

Abstract Cuproptosis, a newly identified form of regulated cell death that is copper‐dependent, offers great opportunities for exploring the use of copper‐based nanomaterials inducing cuproptosis for cancer treatment. Here, a glucose oxidase (GOx)‐engineered nonporous copper(I) 1,2,4‐triazolate ([Cu...

Subject

Glucose oxidase

Photodynamic therapy

Cancer cell

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