The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer

Berchuck, J.E.; Facchinetti, Francesco; DiToro, Daniel; Baiev, Islam; Majeed, Umair; A. Reyes, Sylvia; S. Chen, Christopher; Zhang, Karen; Sharman, R.; Luiz Serrano Usón, Pedro; Maurer, Jochen; T. Shroff, Rachna; C. Pritchard, Colin; Wu, Meng‐Ju; V.T. Catenacci, Daniel; M. Javle, M.; Friboulet, Luc; Hollebecque, Antoine; Bardeesy, Nabeel; X. Zhu, Andrew; K. Lennerz, Jochen; Kye Jyn Tan, Benjamin; J. Borad, Mitesh; R. Parikh, Aparna; A. Kiedrowski, Lesli; Kate Kelley, Robin; Mody, Kabir; Juric, Dejan; Goyal, Love

doi:10.1016/j.annonc.2022.09.150

Public

The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer

Published in Annals of Oncology • Sep 9, 2022

Authors:

J.E. Berchuck

Francesco Facchinetti

Daniel DiToro

Abstract

BACKGROUND: Targeted therapies have transformed clinical management of advanced biliary tract cancer (BTC). Cell-free DNA (cfDNA) analysis is an attractive approach for cancer genomic profiling that overcomes many limitations of traditional tissue-based analysis. We examined cfDNA as a tool to infor...

Subject

Biliary tract cancer

Medicine

Biliary tract

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