Quercetin alleviates kainic acid-induced seizure by inhibiting the Nrf2-mediated ferroptosis pathway.

Ruijin, Xie,; Wenjing, Zhao,; Scott, Lowe,; Rachel, Bentley,; Guoqin, Hu,; Huiya, Mei,; Xiaofan, Jiang,; Chenyu, Sun,; Yu, Wu,; Liu, Yueying

doi:10.1016/j.freeradbiomed.2022.09.001

Public

Quercetin alleviates kainic acid-induced seizure by inhibiting the Nrf2-mediated ferroptosis pathway.

Published in Free radical biology & medicine • Oct 1, 2022

Authors:

Xie, Ruijin

Zhao, Wenjing

Lowe, Scott

Abstract

BACKGROUND: Epilepsy is one of the most common neurological disorders in childhood. However, classical antiepileptic drugs are linked with drug toxicity and cognitive function impairment in children. Hence, it is essential to develop a novel therapy to solve this problem. Currently, studies indicate...

Subject

Cognitive function

Ferroptosis

GPX4

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!