Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

Zhou, Wei; Kanai, Masahiro; Wu, Kuan-Han; Rasheed, Humaira; Tsuo, Kristin; Hirbo, Jibril; Wang, Ying; Bhattacharya, Arjun; Zhao, Huiling; Namba, Shinichi; Surakka, Ida; N. Wolford, Brooke; Lo Faro, Valeria; A. Lopera-Maya, Esteban; Läll, Kristi; Favé, Marie-Julie; Partanen, Juulia; B. Chapman, Sinéad; Karjalainen, Juha; Kurki, Mitja; Maasha, Mutaamba; Brumpton, Ben; Chavan, Sameer; Chen, Tzu‐Ting; Daya, Michelle; Ding, Yi; Anne Feng, Yen‐Chen; Guare, Lindsay; R. Gignoux, Christopher; E. Graham, Sarah; Hornsby, Whitney; Ingold, Nathan; I. Ismail, Said; Johnson, Ruth; Laisk, Triin; Lin, Kuang; Lv, Jun; Y. Millwood, Iona; Moreno–Grau, Sonia; Nam, Kisung; Palta, Priit; Pandit, Anita; Preuß, Michael; Saad, Chadi; Setia-Verma, Shefali; Þorsteinsdóttir, Unnur; Uzunović, Jasmina; Verma, Anurag; Zawistowski, Matthew; Zhong, Xue; Afifi, Nahla; Al-Dabhani, Kawthar; Al Thani, Asma; Bradford, Yuki; Campbell, Archie; Crooks, Kristy; H. de Bock, Geertruida; M. Damrauer, Scott; J. Douville, Nicholas; Finer, Sarah; G. Fritsche, Lars; Fthenou, Eleni; Gonzalez-Arroyo, Gilberto; Griffiths, Chris; Guo, Yu; A. Hunt, Karen; Ioannidis, Alexander; M. Jansonius, Nomdo; Konuma, Takahiro; Ta Michael Lee, Ming; Lopez-Pineda, Arturo; Matsuda, Yuta; E. Marioni, Riccardo; Moatamed, Babak; A. Nava-Aguilar, Marco; Numakura, Kensuke; Patil, Snehal; Rafaels, Nicholas; Richmond, Anne; Rojas‐Muñoz, Agustin; Shortt, Jonathan; Straub, Péter; Tao, Ran; Vanderwerff, Brett; Vernekar, Manvi; Veturi, Yogasudha; C. Barnes, Kathleen; Boezen, Marike; Chen, Zhengming; Chen, Chia‐Yen; H. Cho, Judy; Davey Smith, George; K. Finucane, Hilary; Franke, Lude; R. Gamazon, Eric; Ganna, Andrea; R. Gaunt, Tom; Ge, Tian; Huang, Hailiang; E. Huffman, Jennifer; Katsanis, Nicholas; Koskela, Jukka; Lajonchere, Clara; H. Law, Matthew; Li, Liming; M. Lindgren, Cecilia; J. F. Loos, Ruth; MacGregor, Stuart; Matsuda, Koichi; M. Olsen, Catherine; J. Porteous, David; A. Shavit, Jordan; Snieder, Harold; Takano, Tomohiro; C. Trembath, Richard; M. Vonk, Judith; C. Whiteman, David; J. Wicks, Stephen; Wijmenga, Cisca; Wright, John; Zheng, Jie; Zhou, Xiang; Awadalla, Philip; Boehnke, Michael; D. Bustamante, Carlos; J. Cox, Nancy; Fatumo, Segun; H. Geschwind, Daniel; Hayward, Caroline; Hveem, Kristian; E. Kenny, Eimear; Lee, Seunggeun; Lin, Kuang; Mbarek, Hamdi; Mägi, Reedik; C. Martin, Hilary; E. Medland, Sarah; Okada, Yukinori; Palotie, Aarno; Paşaniuc, Bogdan; J. Rader, Daniel; D. Ritchie, Marylyn; Sanna, Serena; W. Smoller, Jordan; Stefánsson, Kāri; A. van Heel, David; Walters, Robin; Zöllner, Sebastian; R. Martin, Alicia; J. Willer, Cristen; J. Daly, Mark; M. Neale, Benjamin

doi:10.1016/j.xgen.2022.100192

Public

Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

Published in Cell Genomics • Oct 1, 2022

Authors:

Wei Zhou

Masahiro Kanai

Kuan-Han Wu

Abstract

Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry. We introduce the Global Biobank Meta-analysis Initiative (GBMI)-a collaborative ...

Subject

Biobank

Genome-wide association study

Genetic association

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