Discovery of 42 genome-wide significant loci associated with dyslexia.

Doust, Catherine; Fontanillas, Pierre; Eising, Else; D Gordon, Scott; Wang, Zhengjun; Alagöz, Gökberk; Molz, Barbara; Research Team, 23andMe; Trait Working Group of the GenLang Consortium, Quantitative; St Pourcain, Beate; Francks, Clyde; E Marioni, Riccardo; Zhao, Jingjing; Paracchini, Silvia; B Talcott, Joel; P Monaco, Anthony; F Stein, John; R Gruen, Jeffrey; K Olson, Richard; G Willcutt, Erik; C DeFries, John; F Pennington, Bruce; D Smith, Shelley; J Wright, Margaret; G Martin, Nicholas; Auton, Adam; C Bates, Timothy; E Fisher, Simon; Luciano, Michelle

doi:10.1038/s41588-022-01192-y

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Discovery of 42 genome-wide significant loci associated with dyslexia.

Published in Nature genetics • Nov 1, 2022

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Authors:

Catherine Doust

,

Pierre Fontanillas

,

Else Eising

Abstract

Reading and writing are crucial life skills but roughly one in ten children are affected by dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up to 70%, yet few convincing genetic markers have been found. Here we performed a genome-wide association study of ...

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