Haloperidol for the Treatment of Delirium in ICU Patients

Christine Andersen‐Ranberg, Nina; Musaeus Poulsen, Lone; Perner, Anders; Wetterslev, Jørn; Estrup, Stine; Hästbacka, Johanna; Morgan, Matt; Citerio, Giuseppe; Caballero, Jesús; Lange, Theis; N. Kjær, Maj-Brit; H. Ebdrup, Bjørn; Engstrøm, Janus; Harboe Olsen, Markus; Oxenbøll Collet, Marie; Bekker Mortensen, Camilla; Weber, Sven‐Olaf; Sofie Andreasen, Anne; H. Bestle, Morten; Uslu, Bülent; Scharling Pedersen, Helle; Gramstrup Nielsen, Louise; Christian Boesen, Hans; V. Jensen, Jacob; Nebrich, Lars; la Cour, Kirstine; Laigaard, Jens; Haurum, Cecilie; W. Olesen, Marie; Overgaard‐Steensen, Christian; Westergaard, Bo; Brand, Björn; Kingo Vesterlund, Gitte; Thornberg Kyhnauv, Pernille; Sommer Mikkelsen, Vibe; Hyttel-Sørensen, Simon; de Haas, Inge; Rosborg Aagaard, Søren; O. Nielsen, Line; Sofie Broberg Eriksen, Anne; Steen Rasmussen, Bodil; Brix, Helene; Hildebrandt, Thomas; Schønemann‐Lund, Martin; Fjeldsøe-Nielsen, Hans; Kuivalainen, Anna‐Maria; Mathiesen, Ole

doi:10.1056/nejmoa2211868

Public

Haloperidol for the Treatment of Delirium in ICU Patients

Published in New England Journal of Medicine • Oct 26, 2022

Authors:

Nina Christine Andersen‐Ranberg

Lone Musaeus Poulsen

Anders Perner

Abstract

BACKGROUND: Haloperidol is frequently used to treat delirium in patients in the intensive care unit (ICU), but evidence of its effect is limited. METHODS: In this multicenter, blinded, placebo-controlled trial, we randomly assigned adult patients with delirium who had been admitted to the ICU for an...

Subject

Delirium

Haloperidol

Medicine

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