A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue

Crielaard, Hanneke; Guvenir Torun, Su; B. Wissing, Tamar; de Miguel Muñoz, Pablo; Kremers, Gert‐Jan; Gijsen, Frank; Van der Heiden, Kim; C. Akyildiz, Ali

doi:10.3791/64334

Public

A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue

Published in Journal of Visualized Experiments • Nov 11, 2022

Authors:

Hanneke Crielaard

Su Guvenir Torun

Tamar B. Wissing

Abstract

The rupture of atherosclerotic plaques in coronary and carotid arteries is the primary cause of fatal cardiovascular events. However, the rupture mechanics of the heterogeneous, highly collagenous plaque tissue, and how this is related to the tissue's fibrous structure, are not known yet. Existing p...

Subject

Fibrous cap

Digital image correlation

Collagen fiber

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