High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer

Salcher, Stefan; Sturm, Gregor; Horvath, Lena; Untergasser, Gerold; Kuempers, Christiane; Fotakis, Georgios; Panizzolo, Elisa; Martowicz, Agnieszka; Trebo, Manuel; Pall, Georg; Gamerith, Gabriele; Sykora, Martina; Augustin, Florian; Schmitz, Katja; Finotello, Francesca; Rieder, Dietmar; Perner, Sven; Sopper, Sieghart; Wolf‎, Dominik; Pircher, Andreas; Trajanoski, Zlatko

doi:10.1016/j.ccell.2022.10.008

Public

High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer

Published in Cancer Cell • Nov 10, 2022

Authors:

Stefan Salcher

Gregor Sturm

Lena Horvath

Abstract

Non-small cell lung cancer (NSCLC) is characterized by molecular heterogeneity with diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and resistance. However, full understanding of how immune cell phenotypes vary across different patient subgroups is lacking. He...

Subject

Biology

Cell

Single-cell analysis

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