Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial

Carles Trullàs, Joan; Luís Morales‐Rull, José; Casado, Jesús; Carrera‐Izquierdo, Margarita; Sánchez‐Marteles, Marta; Conde‐Martel, Alicia; Francisco Dávila‐Ramos, Melitón; Llàcer, Pau; Salamanca‐Bautista, Prado; Pérez-Silvestre, José; Ángel Plasín, Miguel; Manuel Cerqueiro, José; Gil, Paloma; Formiga, Francesç; Manzano, Luís; trial investigators, CLOROTIC; L. Morales, José; Solé, Cristina; Carrera, Margarita; León, Marta; García Sánchez, Marta; Garcés‐Horna, Vanesa; Conde, Alicia; Hernández Meneses, Marta; Fco Dávila, Melitón; Hernández-Carballo, Carolina; Casado, Jesús; Pedro Zabaleta, Juan; Llácer Iborra, Pau; Carmen Moreno García, Mari; Carles Trullàs, Joan; Bisbe, Josep; del Prado Salamanca Bautista, María; Aramburu Bodas, Óscar; Manzano, Luís; Ruiz, Raúl; Pérez-Silvestre, José; Ángel Plasín, Miguel; González, J.; Chivite, David; Formiga, Francesç; Gil, Paloma; Jordana, R.; Villalonga, María; Inmaculada Páez Rubio, M; Ma Cepeda Rodrigo, José; Montero Pérez‐Barquero, Manuel; Muela, Alberto; Mateos, Lourdes; Manubens Grau, Jordi; Armengou, A.; Herrero, Almudena; Quirós López, Raúl

doi:10.1093/eurheartj/ehac689

Public

Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial

Published in European Heart Journal • Nov 24, 2022

Authors:

Joan Carles Trullàs

José Luís Morales‐Rull

Jesús Casado

Abstract

AIMS: To evaluate whether the addition of hydrochlorothiazide (HCTZ) to intravenous furosemide is a safe and effective strategy for improving diuretic response in acute heart failure (AHF). METHODS AND RESULTS: A prospective, double-blind, placebo-controlled trial, including patients with AHF random...

Subject

Medicine

Hydrochlorothiazide

Furosemide

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