Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial

Carles Trullàs, Joan; Luis Morales-Rull, José; Casado, Jesús; Carrera-Izquierdo, Margarita; Sánchez-Marteles, Marta; Conde-Martel, Alicia; Francisco Dávila-Ramos, Melitón; Llácer, Pau; Salamanca-Bautista, Prado; Pérez-Silvestre, José; Ángel Plasín, Miguel; Manuel Cerqueiro, José; Gil, Paloma; Formiga, Francesc; Manzano, Luis; trial investigators, CLOROTIC; Luís Morales, José; Solé, Cristina; Carrera, Margarita; León, Marta; Sánchez, Marta; Garcés Horna, Vanesa; Conde, Alicia; Hernández Meneses, Marta; Fco Dávila, Melitón; Hernández Carballo, Carolina; Casado, Jesús; Pedro Zabaleta, Juan; Llàcer Iborra, Pau; Carmen Moreno García, Mari; Carles Trullàs, Joan; Bisbe, Josep; del Prado Salamanca Bautista, María; Aramburu Bodas, Óscar; Manzano, Luís; Ruiz, Raúl; Pérez Silvestre, José; Ángel Plasín, Miguel; Manuel Cerqueiro González, José; Chivite, David; Formiga, Francesc; Gil, Paloma; Jordana, Rosa; Villalonga, María; Inmaculada Páez Rubio, M; Mª Cepeda Rodrigo, José; Montero Pérez-Barquero, Manuel; Muela, Alberto; Mateos, Lourdes; Grau, Jordi; Armengou, Arola; Herrero, Almudena; Quirós López, Raúl

doi:10.1093/eurheartj/ehac689

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Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial

Shared by NobleBlocks on Nov 24, 2022 • 12:00 AM UTC

Authors:

Joan Carles Trullàs

José Luis Morales-Rull

Jesús Casado

Abstract

Abstract Aims To evaluate whether the addition of hydrochlorothiazide (HCTZ) to intravenous furosemide is a safe and effective strategy for improving diuretic response in acute heart failure (AHF). Methods and results A prospective, double-blind, placebo-controlled trial, including patients with AHF...

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