LATE-NC staging in routine neuropathologic diagnosis: an update

T. Nelson, Peter; B. Lee, Edward; D. Cykowski, Matthew; Alafuzoff, Irina; Arfanakis, Konstantinos; Attems, Johannes; Brayne, Carol; M. Corrada, María; N. Dugger, Brittany; E. Flanagan, Margaret; Ghetti, Bernardino; T. Grinberg, Lea; Grossman, Murray; J. Grothe, Michel; M. Halliday, Glenda; Hasegawa, Masato; R. K. Hokkanen, Suvi; Hunter, Sally; A. Jellinger, K.; H. Kawas, Claudia; Dirk Keene, C.; Kouri, Naomi; G. Kovács, Gábor; B. Leverenz, James; S. Latimer, Caitlin; R. Mackenzie, Ian; Mao, Qinwen; E. McAleese, Kirsty; L. Merrick, Richard; J. Montine, Thomas; E. Murray, Melissa; Myllykangas, Liisa; Nag, Sukriti; H. Neltner, Janna; L. Newell, Kathy; A. Rissman, Robert; Saito, Yuko; Ahmad Sajjadi, S.; E. Schwetye, Katherine; F. Teich, Andrew; Rudolf Thal, Dietmar; O. Tomé, Sandra; C. Troncoso, Juan; J. Wang, Shih‐Hsiu; L. White, Charles; Wısnıewskı, Thomas; Yang, Hyun‐Sik; A. Schneider, Julie; W. Dickson, Dennis; Neumann, Manuela

doi:10.1007/s00401-022-02524-2

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LATE-NC staging in routine neuropathologic diagnosis: an update

Published in Acta Neuropathologica • Dec 13, 2022

Authors:

Peter T. Nelson

Edward B. Lee

Matthew D. Cykowski

Abstract

An international consensus report in 2019 recommended a classification system for limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes (LATE-NC). The suggested neuropathologic staging system and nomenclature have proven useful for autopsy practice and dementia research. Howev...

Subject

Frontotemporal lobar degeneration

Amyotrophic lateral sclerosis

Medical diagnosis

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