Microglia regulate central nervous system myelin growth and integrity

B. McNamara, Niamh; A. D. Munro, David; Bestard-Cuche, Nadine; Uyeda, Akiko; F. J. Bogie, Jeroen; Hoffmann, Alana; Holloway, R.; Molina-González, Irene; E. Askew, Katharine; Mitchell, Stephen; Mungall, William; Dodds, Michael; Dittmayer, Carsten; Moss, Jonathan; Rose, Jamie; Szymkowiak, Stefan; Amann, Lukas; W. McColl, Barry; Prinz, Marco; L. Spires‐Jones, Tara; Stenzel, Werner; Horsburgh, Karen; J. A. Hendriks, Jerome; Pridans, Clare; Muramatsu, Rieko; Williams, Anna; Priller, Josef; E. Miron, Véronique

doi:10.1038/s41586-022-05534-y

Public

Microglia regulate central nervous system myelin growth and integrity

Published in Nature • Dec 14, 2022

Authors:

Niamh B. McNamara

David A. D. Munro

Nadine Bestard-Cuche

Abstract

Abstract Myelin is required for the function of neuronal axons in the central nervous system, but the mechanisms that support myelin health are unclear. Although macrophages in the central nervous system have been implicated in myelin health 1 , it is unknown which macrophage populations are involve...

Subject

Myelin

Microglia

Central nervous system

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