GD2 Expression in Medulloblastoma and Neuroblastoma for Personalized Immunotherapy: A Matter of Subtype

Paret, Claudia; Ustjanzew, Arsenij; Ersali, Sara; Seidmann, Larissa; Jennemann, Richard; Ziegler, Nicole; El Malki, Khalifa; Russo, Alexandra; Wingerter, Arthur; Ortmüller, Franziska; Bornas, Angelina; Charlotte Wehling, Pia; Lepădatu, Adina; Ottenhausen, Malte; Roth, Wilfried; Sommer, Clemens; Fliß, Barbara; Frauenknecht, Katrin; Sandhoff, Roger; Faber, Jörg

doi:10.3390/cancers14246051

Public

GD2 Expression in Medulloblastoma and Neuroblastoma for Personalized Immunotherapy: A Matter of Subtype

Published in Cancers • Dec 8, 2022

Authors:

Claudia Paret

Arsenij Ustjanzew

Sara Ersali

Abstract

Neuroblastoma (NBL) and medulloblastoma (MB) are aggressive pediatric cancers which can benefit from therapies targeting gangliosides. Therefore, we compared the ganglioside profile of 9 MB and 14 NBL samples by thin layer chromatography and mass spectrometry. NBL had the highest expression of GD2 (...

Subject

Medulloblastoma

Neuroblastoma

Ganglioside

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