Study on the relationship between genetic polymorphism of reductive folic acid carrier and the risk of neural tube defects

Yang, Xusen; Fan, Guofeng; Wang, Zengliang; Li, Shaoshan; Qin, Hu; Wang, Yun; Wang, Yun; Ma, Xiaohu; Ji, Wenyu; Wang, Yongxin; Wang, Yongxin

doi:10.1007/s00381-022-05805-z

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Study on the relationship between genetic polymorphism of reductive folic acid carrier and the risk of neural tube defects

Published in Child s Nervous System • Dec 20, 2022

Authors:

Xusen Yang

Guofeng Fan

Zengliang Wang

Abstract

BACKGROUND: To investigate the association of folate metabolism gene polymorphism with neural tube defects (NTDs) in Chinese population. METHODS: The subjects were divided into two groups, 495 children with NTDs (NTD group) and 255 healthy children (control group). RESULTS: The levels of folic acid,...

Subject

Methylenetetrahydrofolate reductase

Neural tube

Medicine

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