The role of IL-6/JAK2/STAT3 signaling pathway in cancers

Huang, Bei; Lang, Xiaoling; Li, Xihong

doi:10.3389/fonc.2022.1023177

Public

The role of IL-6/JAK2/STAT3 signaling pathway in cancers

Published in Frontiers in Oncology • Dec 16, 2022

Authors:

Bei Huang

Xiaoling Lang

Xihong Li

Abstract

Interleukin-6 (IL-6) is a pleiotropic cytokine involved in immune regulation. It can activate janus kinase 2 (JAK2)-signal transducer and activator of transcription 3 (STAT3) signaling pathway. As one of the important signal transduction pathways in cells, JAK2/STAT3 signaling pathway plays a critic...

Subject

STAT3

Signal transduction

Cancer research

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