Integrative systems immunology uncovers molecular networks of the cell cycle that stratify COVID‐19 severity

Aliane de Souza Prado, Caroline; Leandro M. Fonseca, Dennyson; Singh, Youvika; Salerno Filgueiras, Igor; Baiocchi, G.; Rodrigues Plaça, Desirée; H. C. Marques, Alexandre; Costa Silva Dantas‐Komatsu, Raquel; Nakanishi Usuda, Júlia; Paccielli Freire, Paula; Coelho Salgado, Ranieri; Maria da Silva Napoleão, Sarah; Nalio Ramos, Rodrigo; Rocha, Vanderson; Zhou, Guangyan; Catar, Rusan; Moll, Guido; Olsen Saraiva Câmara, Niels; Cabral de Miranda, Gustavo; Lúcia Garcia Calich, Vera; M. Giil, Lasse; Mishra, Neha; Tran, Florian; Ducati Luchessi, André; I. Nakaya, Helder; D. Ochs, Hans; Jurišica, Igor; F. Schimke, Lena; Cabral-Marques, Otávio

doi:10.1002/jmv.28450

Public

Integrative systems immunology uncovers molecular networks of the cell cycle that stratify COVID‐19 severity

Published in Journal of Medical Virology • Jan 4, 2023

Authors:

Caroline Aliane de Souza Prado

Dennyson Leandro M. Fonseca

Youvika Singh

Abstract

Several perturbations in the number of peripheral blood leukocytes, such as neutrophilia and lymphopenia associated with Coronavirus disease 2019 (COVID-19) severity, point to systemic molecular cell cycle alterations during severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. How...

Subject

Cell cycle

Biology

Transcriptome

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