A mitochondria-localized iridium(
                    <scp>iii</scp>
                    ) photosensitizer for two-photon photodynamic immunotherapy against melanoma

Wang, Lili; Karges, Johannes; Wei, Fangmian; Xie, Lina; Chen, Zhuoli; Gasser, Gilles; Ji, Liangnian; Chao, Hui

doi:10.1039/d2sc06675k

Public

A mitochondria-localized iridium( iii ) photosensitizer for two-photon photodynamic immunotherapy against melanoma

Shared by NobleBlocks on Jan 1, 2023 • 12:00 AM UTC

Authors:

Lili Wang

Johannes Karges

Fangmian Wei

Abstract

An iridium( iii ) two-photon photosensitizer was demonstrated to effectively trigger melanoma cell death by a combination of ferroptosis and ICD, and also cause the systemic induction of an immune response.

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