<i>In situ</i> architecture of Opa1-dependent mitochondrial cristae remodeling

Y. Fry, Michelle; P. Navarro, Paula; Hakim, Pusparanee; VY, Ananda; Qin, Xingping; C. Landoni, Juan; Rath, Sneha; Inde, Zintis; Makhlouta Lugo, Camila; E Luce, Bridget; Ge, Yifan; L. McDonald, Julie; Ali, Ilzat; L. Ha, Leillani; P. Kleinstiver, Benjamin; C. Chan, David; A. Sarosiek, Kristopher; H. Chao, Luke

doi:10.1101/2023.01.16.524176

Public

In situ architecture of Opa1-dependent mitochondrial cristae remodeling

Published in bioRxiv (Cold Spring Harbor Laboratory) • Jan 18, 2023

Authors:

Michelle Y. Fry

Paula P. Navarro

Pusparanee Hakim

Abstract

Abstract Cristae membrane state plays a central role in regulating mitochondrial function and cellular metabolism. The protein Optic atrophy 1 (Opa1) is an important crista remodeler that exists as two forms in the mitochondrion, a membrane-anchored long form (l-Opa1) and a processed short form (s-O...

Subject

Crista

Mitochondrion

Cell biology

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