Faeces‐derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases

Fizanne, Lionel; Villard, Alexandre; Benabbou, Nadia; Recoquillon, Sylvain; Soleti, Raffaella; Delage, Erwan; Wertheimer, Mireille; Vidal‐Gómez, Xavier; Oullier, Thibauld; Chaffron, Samuel; Carmen Martínez, Maria; Neunlist, Michel; Boursier, Jérôme; Andriantsitohaina, Ramaroson

doi:10.1002/jev2.12303

Public

Faeces‐derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases

Published in Journal of Extracellular Vesicles • Jan 28, 2023

Authors:

Lionel Fizanne

Alexandre Villard

Nadia Benabbou

Abstract

The role of extracellular vesicles (EVs) from faeces (fEVs) and small circulating EVs (cEVs) in liver diseases such as non-alcoholic fatty diseases (NAFLD) and non-alcoholic steatohepatitis (NASH) has not been demonstrated. fEVs and cEVs of healthy donors, NAFLD and NASH patients were isolated and c...

Subject

Biology

Proinflammatory cytokine

Steatohepatitis

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