Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE

Gaba, Prakriti; L. O’Donoghue, Michelle; Park, Jeong‐Gun; D. Wiviott, Stephen; Atar, Dan; Kuder, Julia; Im, KyungAh; A. Murphy, Sabina; Maria De Ferrari, Gaetano; Gaciong, Zbigniew; Tóth, Kálmán; Gouni‐Berthold, Ioanna; López‐Miranda, José; Schiele, François; Mach, François; H. Flores‐Arredondo, Jose; Antonio G. López, J.; Elliott‐Davey, Mary; Wang, Bei; Laura Monsalvo, Maria; Abbasi, Siddique; P. Giugliano, Robert; S. Sabatine, Marc

doi:10.1161/circulationaha.122.063399

Public

Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE

Published in Circulation • Feb 13, 2023

Authors:

Prakriti Gaba

Michelle L. O’Donoghue

Jeong‐Gun Park

Abstract

Background: Low-density lipoprotein cholesterol (LDL-C) is a well-established risk factor for atherosclerotic cardiovascular disease. However, the optimal achieved LDL-C level with regard to efficacy and safety in the long term remains unknown. Methods: In FOURIER (Further Cardiovascular Outcomes Re...

Subject

Medicine

Evolocumab

Internal medicine

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