The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia

Nichols, Emma; L. Merrick, Richard; I Hay, Simon; Himali, Dibya; J. Himali, Jayandra; Hunter, Sally; A. D. Keage, Hannah; S. Latimer, Caitlin; R. Scott, Matthew; D Steinmetz, Jaimie; M. Walker, Jamie; B. Wharton, Stephen; D. Wiedner, Crystal; K. Crane, Paul; Dirk Keene, C.; J. Launer, Lenore; E. Matthews, Fiona; A. Schneider, Julie; Seshadri, Sudha; R. White, Lon; Brayne, Carol; Vos, Theo

doi:10.1016/s2666-7568(23)00019-3

Public

The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia

Published in The Lancet Healthy Longevity • Mar 1, 2023

Authors:

Emma Nichols

Richard L. Merrick

Simon I Hay

Abstract

BACKGROUND: Population-based autopsy studies provide valuable insights into the causes of dementia but are limited by sample size and restriction to specific populations. Harmonisation across studies increases statistical power and allows meaningful comparisons between studies. We aimed to harmonise...

Subject

Arteriolosclerosis

Neuropathology

Cerebral amyloid angiopathy

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