Progression of clinical markers in prodromal Parkinson’s disease and dementia with Lewy bodies: a multicentre study

Joza, Stephen; T Hu, Michele; Jung, Ki‐Young; Kunz, Dieter; Stefani, Ambra; Dušek, Petr; Terzaghi, Michele; Arnaldi, Dario; Videnović, Aleksandar; C. Schiess, Mya; Hermann, Wiebke; Lee, Jee‐Young; Ferini‐Strambi, Luigi; J.G. Lewis, Simon; Leclair‐Visonneau, Laurène; H. Oertel, Wolfgang; Antelmi, Elena; Sixel‐Döring, Friederike; Cochen De Cock, Valérie; Liguori, Claudio; Liu, Jun; Provini, Federica; Puligheddu, Monica; Nicoletti, Alessandra; L. Bassetti, Claudio; Bušková, Jitka; Dauvilliers, Yves; Ferri, Raffaele; Montplaisir, Jacques; Lawton, Michael; Kim, Han‐Joon; Bes, Frédérik; Högl, Birgit; Šonka, Karel; Fiamingo, Giuseppe; Mattioli, Pietro; L. Lavadia, Maria; Suescun, Jessika; Ah Woo, Kyung; Marelli, Sara; A. Ehgoetz Martens, Kaylena; Janzen, Annette; Plazzi, Giuseppe; Mollenhauer, Brit; Fernandes, Mariana; Li, Yuanyuan; Cortelli, Pietro; Figorilli, Michela; Edoardo Cicero, Calogero; Schaefer, Carolin; Guiraud, Lily; Lanza, Giuseppe; Gagnon, Jean‐François; Sunwoo, Jun‐Sang; Ibrahim, Abubaker; Girtler, Nicola; Trenkwalder, Claudia; Baldelli, Luca; Pelletier, Amélie; B. Postuma, Ronald; the International REM Sleep Behavior Disorder Study Group, for

doi:10.1093/brain/awad072

Public

Progression of clinical markers in prodromal Parkinson’s disease and dementia with Lewy bodies: a multicentre study

Published in Brain • Mar 7, 2023

Authors:

Stephen Joza

Michele T Hu

Ki‐Young Jung

Abstract

The neurodegenerative synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are characterized by a typically lengthy prodromal period of progressive subclinical motor and non-motor manifestations. Among these, idiopathic REM sleep behaviour disorder is a powerful early pred...

Subject

Dementia with Lewy bodies

REM sleep behavior disorder

Dementia

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