Strategies targeting PD-L1 expression and associated opportunities for cancer combination therapy

Yin, Shuangneng; Chen, Zhaojun; Chen, Dugang; Yan, Dan

doi:10.7150/thno.80091

Public

Strategies targeting PD-L1 expression and associated opportunities for cancer combination therapy

Published in Theranostics • Jan 1, 2023

Authors:

Shuangneng Yin

Zhaojun Chen

Dugang Chen

Abstract

Immunotherapy has achieved great success recently and opened a new avenue for anti-tumor treatment. Programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) are typical immune checkpoints that transmit coinhibitory signals, muting the host immunity. Monoclonal antibodies that block PD-1/P...

Subject

Immunotherapy

PD-L1

Tumor microenvironment

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