Inferring spatial transcriptomics markers from whole slide images to characterize metastasis-related spatial heterogeneity of colorectal tumors: A pilot study

Fatemi, Michael; Feng, Eric; Sharma, Cyril; Azher, Zarif; Goel, Tarushii; A. Ramwala, Ojas; Palisoul, Scott; E. Barney, Rachael; Perreard, Laurent; Kolling, Fred; A. Salas, Lucas; C. Christensen, Brock; J. Tsongalis, Gregory; Vaickus, Louis; Levy, Joshua

doi:10.1016/j.jpi.2023.100308

Public

Inferring spatial transcriptomics markers from whole slide images to characterize metastasis-related spatial heterogeneity of colorectal tumors: A pilot study

Published in Journal of Pathology Informatics • Jan 1, 2023

Authors:

Michael Fatemi

Eric Feng

Cyril Sharma

Abstract

Over 150 000 Americans are diagnosed with colorectal cancer (CRC) every year, and annually over 50 000 individuals will die from CRC, necessitating improvements in screening, prognostication, disease management, and therapeutic options. Tumor metastasis is the primary factor related to the risk of r...

Subject

Spatial heterogeneity

Computer science

Tumour heterogeneity

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