Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials

Corren, Jonathan; Menzies‐Gow, Andrew; Chupp, Geoffrey; Israel, Elliot; Korn, Stephanie; Cook, Bill; S. Ambrose, Christopher; Hellqvist, Åsa; L. Roseti, Stephanie; A. Molfino, Néstor; Llanos, Jean‐Pierre; Martin, Neil; Bowen, Karin; M. Griffiths, Janet; R. Parnes, Jane; Colice, Gene

doi:10.1164/rccm.202210-2005oc

Public

Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials

Published in American Journal of Respiratory and Critical Care Medicine • Apr 4, 2023

Authors:

Jonathan Corren

Andrew Menzies‐Gow

Geoffrey Chupp

Abstract

Abstract Rationale Tezepelumab reduced exacerbations in patients with severe, uncontrolled asthma across a range of baseline blood eosinophil counts and fractional exhaled nitric oxide levels, and irrespective of allergy status, in the phase 2b PATHWAY (Study to Evaluate the Efficacy and Safety of M...

Subject

Medicine

Asthma

Exacerbation

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