Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults

E. Walsh, Edward; Pérez Marc, Gonzalo; Zareba, Agnieszka; R. Falsey, Ann; Jiang, Qin; Quinn Patton, Michael; P. Polack, Fernando; J. Llapur, Conrado; A. Doreski, Pablo; Ilangovan, Kumar; Rämet, Mika; Fukushima, Yasushi; Hussen, Nazreen; Bont, Louis; F Cardona, Jose; DeHaan, Elliot; Castillo Villa, Giselle; Ingilizova, Marinela; Eiras, Daniel; Mikati, Tarek; N. Shah, Rupal; Schneider, Katherine; Cooper, David; Koury, Kenneth; Lino, Maria-Maddalena; S. Anderson, Annaliesa; U. Jansen, Kathrin; A. Swanson, Kena; Gurtman, Alejandra; C. Gruber, William; Schmöele-Thoma, Beate

doi:10.1056/nejmoa2213836

Public

Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults

Published in New England Journal of Medicine • Apr 5, 2023

Authors:

Edward E. Walsh

Gonzalo Pérez Marc

Agnieszka Zareba

Abstract

BACKGROUND: Respiratory syncytial virus (RSV) infection causes considerable illness in older adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein-based (RSVpreF) vaccine in this population are unknown. METHODS: In this ongoing, phase 3 trial, we randomly assigned, i...

Subject

Bivalent (engine)

Virology

Medicine

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