Symptomatology in 4-repeat tauopathies is associated with data-driven topology of [18F]-PI-2620 tau-PET signal

Schönecker, Sonja; Palleis, Carla; Franzmeier, Nicolai; Katzdobler, Sabrina; Ferschmann, Christian; Schuster, Sebastian; Finze, Anika; Scheifele, Maximilian; Prix, Catharina; M. Fietzek, Urban; Weidinger, Endy; Nübling, Georg; Vöglein, Jonathan; Patt, Marianne; Barthel, Henryk; Sabri, Osama; Danek, Adrian; U. Höglinger, Günter; Brendel, Matthias; Levin, Johannes

doi:10.1016/j.nicl.2023.103402

Public

Symptomatology in 4-repeat tauopathies is associated with data-driven topology of [18F]-PI-2620 tau-PET signal

Published in NeuroImage Clinical • Jan 1, 2023

Authors:

Sonja Schönecker

Carla Palleis

Nicolai Franzmeier

Abstract

In recent years in vivo visualization of tau deposits has become possible with various PET radiotracers. The tau tracer [18F]PI-2620 proved high affinity both to 3-repeat/4-repeat tau in Alzheimer’s disease as well as to 4-repeat tau in progressive supranuclear palsy (PSP) and corticobasal syndrome ...

Subject

Progressive supranuclear palsy

Tauopathy

Anterior cingulate cortex

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!