The evolution of lung cancer and impact of subclonal selection in TRACERx.

AM, Frankell; M, Dietzen; Bakir M, Al; EL, Lim; T, Karasaki; S, Ward; S, Veeriah; E, Colliver; A, Huebner; A, Bunkum; MS, Hill; K, Grigoriadis; DA, Moore; JRM, Black; WK, Liu; K, Thol; O, Pich; TBK, Watkins; C, Naceur-Lombardelli; DE, Cook; R, Salgado; GA, Wilson; C, Bailey; M, Angelova; R, Bentham; C, Martínez-Ruiz; C, Abbosh; AG, Nicholson; Quesne J, Le; D, Biswas; R, Rosenthal; C, Puttick; S, Hessey; C, Lee; P, Prymas; A, Toncheva; J, Smith; W, Xing; J, Nicod; G, Price; KM, Kerr; B, Naidu; G, Middleton; KG, Blyth; DA, Fennell; MD, Forster; SM, Lee; M, Falzon; M, Hewish; MJ, Shackcloth; E, Lim; S, Benafif; P, Russell; E, Boleti; MG, Krebs; JF, Lester; D, Papadatos-Pastos; T, Ahmad; RM, Thakrar; D, Lawrence; N, Navani; SM, Janes; C, Dive; FH, Blackhall; Y, Summers; J, Cave; T, Marafioti; J, Herrero; SA, Quezada; KS, Peggs; RF, Schwarz; Loo P, Van; DM, Miedema; NJ, Birkbak; CT, Hiley; A, Hackshaw; S, Zaccaria; M, Jamal-Hanjani; N, McGranahan; C, Swanton

doi:10.1038/s41586-023-05783-5

Public

The evolution of lung cancer and impact of subclonal selection in TRACERx.

Shared by NobleBlocks on Apr 12, 2023 • 12:00 AM UTC

Authors:

Frankell AM

Dietzen M

Al Bakir M

Abstract

Lung cancer is the leading cause of cancer-associated mortality worldwide1. Here we analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients with non-small cell lung cancer prospectively enrolled into the TRACERx study. This project aims to decipher lung cance...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!