Body composition and lung cancer-associated cachexia in TRACERx

Al‐Sawaf, Othman; Weiss, Jakob; Skrzypski, Marcin; Min Lam, Jie; Karasaki, Takahiro; Zambrana, Francisco; Kidd, Andrew; M. Frankell, Alexander; B.K. Watkins, Thomas; Martínez‐Ruiz, Carlos; Puttick, Clare; R. Black, James; Huebner, Ariana; Al Bakir, Maise; Sokač, Mateo; M. Collins, Susie; Veeriah, Selvaraju; Magno, Neil; Naceur‐Lombardelli, Cristina; Prymas, Paulina; Toncheva, Antonia; Ward, Sophia; Jayanth, Nick; Salgado, Roberto; P. Bridge, Christopher; C. Christiani, David; H. Mak, Raymond; Bay, Camden; H. Rosenthal, Michael; Sattar, Naveed; Welsh, Paul; Liu, Ying; Perrimon, Norbert; Popuri, Karteek; Faisal Beg, Mirza; McGranahan, Nicholas; Hackshaw, Allan; M. Breen, Danna; O’Rahilly, Stephen; J. Birkbak, Nicolai; J.W.L. Aerts, Hugo; B.K. Watkins, Thomas; J. Birkbak, Nicolai; J.W.L. Aerts, Hugo; Lester, J.F.; Bajaj, Amrita; Nakas, Apostolos; Sodha-Ramdeen, Azmina; Ang, Keng; Tufail, Mohamad; Fiyaz Chowdhry, Mohammed; Scotland, Molly; Boyles, Rebecca; Rathinam, Sridhar; Wilson, Claire; Marrone, Domenic; Dulloo, Sean; A. Fennell, Dean; Matharu, Gurdeep; Shaw, Jacqui; Riley, Joan; Primrose, Lindsay; Boleti, Ekaterini; Cheyne, Heather; Khalil, Mohammed; Richardson, Shirley; Cruickshank, Tracey; Price, Gillian; M. Kerr, Keith; Benafif, Sarah; Gilbert, Kayleigh; Naidu, Babu; J. Patel, Akshay; Osman, Aya; Lacson, Christer; Langman, Gerald; Shackleford, Helen; Djearaman, Madava; Kadiri, Salma; Middleton, Gary; Leek, Angela; Davies Hodgkinson, Jack; Totten, Nicola; Montero, Ángeles; Smith, Elaine; Fontaine, Eustace; Granato, Felice; Doran, Helen; Novasio, Juliette; Rammohan, Kendadai; Dennis Joseph, Leena; Bishop, Paul; Shah, Rajesh; Moss, Stuart; Joshi, Vijay; Crosbie, Philip; Gomes, Fábio; Brown, Kate; Carter, Mathew; Chaturvedi, Anshuman; Priest, Lynsey; Oliveira, Pedro; R. Lindsay, Colin; Blackhall, Fiona; Krebs, Matthew; Summers, Yvonne; Clipson, Alexandra; Tugwood, Jonathan; Kerr, Alastair; G. Rothwell, Dominic; Kilgour, Elaine; Dive, Caroline; F. Schwarz, Roland; L. Kaufmann, Tom; A. Wilson, Gareth; Rosenthal, Rachel; Van Loo, Peter; Szállási, Zoltán; Kisistók, Judit; Sokač, Mateo; Dióssy, Miklós; Demeulemeester, Jonas; Bunkum, Abigail; Stewart, Aengus; Magness, Alastair; Rowan, Andrew; Karamani, Angeliki; Chain, Benny; Campbell, Brittany; Castignani, Carla; Bailey, Chris; Abbosh, Christopher; E. Weeden, Clare; Lee, Claudia; Richard, Corentin; T. Hiley, Crispin; A. Moore, David; R. Pearce, David; Karagianni, Despoina; Biswas, Dhruva; Levi, Dina; Hoxha, Elena; Larose Cadieux, Elizabeth; L. Lim, Emilia; Colliver, Emma; Nye, Emma; Grönroos, Eva; Gálvez-Cancino, Felip; Athanasopoulou, Foteini; Gimeno-Valiente, Francisco; Kassiotis, George; Stavrou, Georgia; Mastrokalos, Gerasimos; Zhai, Hao-Ran; L. Lowe, Helen; Matos, Ignacio; Goldman, Jacki; L. Reading, James; Herrero, Javier; K. Rane, Jayant; Nicod, Jérôme; A. Hartley, John; S. Peggs, Karl; S.S. Enfield, Katey; Selvaraju, Kayalvizhi; Thol, Kerstin; Litchfield, Kevin; W. Ng, Kevin; Chen, Kezhong; K. 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Spanswick, Victoria; Barbè, Vittorio; Lu, Wei-Ting; Hill, William; Kin Liu, Wing; Wu, Yin; Naito, Yutaka; Ramsden, Zoe; Veiga, Catarina; Royle, Gary; Collins‐Fekete, Charles‐Antoine; Fraioli, Francesco; Ashford, Paul; Clark, Tristan; Förster, Martin; Ming Lee, Siow; Borg, Elaine; Falzon, Mary; Papadatos-Pastos, Dionysis; M. Wilson, James; Ahmad, Tanya; James Procter, Alexander; Ahmed, Asia; N. Taylor, Magali; Nair, Arjun; Lawrence, David; Patrini, Davide; Navani, Neal; M. Thakrar, Ricky; M. Janes, Sam; Martinoni Hoogenboom, Emilie; Monk, Fleur; W. Holding, James; Choudhary, Junaid; Bhakhri, Kunal; Scarci, Marco; Hayward, Martin; Panagiotopoulos, Nikolaos; Gorman, Pat; Khiroya, Reena; Stephens, Robert; Ning Sophia Wong, Yien; Bandula, Steve; Sharp, Abigail; Smith, Sean; Gower, Nicole; Kaur Dhanda, Harjot; S. Chan, Kitty; Pilotti, Camilla; Leslie, Rachel; Grapa, Anca; Zhang, Hanyun; AbdulJabbar, Khalid; Pan, Xiaoxi; Yuan, Yinyin; Chuter, David; MacKenzie, Mairead; Chee, Serena; Alzetani, Aiman; Cave, Judith; Scarlett, Lydia; Richards, Jennifer; Ingram, Papawadee; Austin, Silvia; Lim, Eric; De Sousa, Paulo; Jordan, Simon; Rice, Alexandra; Raubenheimer, Hilgardt; Bhayani, Harshil; Ambrose, Lyn; Devaraj, Anand; Chavan, Hema; Begum, Sofina; Buderi, Silviu; Kaniu, Daniel; Malima, Mpho; Booth, Sarah; G. Nicholson, Andrew; Fernandes, Nadia; Shah, Pratibha; Proli, Chiara; Hewish, Madeleine; Danson, Sarah; Shackcloth, Michael; Robinson, Lily; Russell, Peter; G. Blyth, Kevin; Dick, Craig; Le Quesne, John; Kirk, Alan; Asif, Mo; Bilancia, Rocco; Kostoulas, Nikos; Thomas, Mathew; Jamal‐Hanjani, Mariam; Swanton, Charles

doi:10.1038/s41591-023-02232-8

Public

Body composition and lung cancer-associated cachexia in TRACERx

Published in Nature Medicine • Apr 1, 2023

Authors:

Othman Al‐Sawaf

Jakob Weiss

Marcin Skrzypski

Abstract

Cancer-associated cachexia (CAC) is a major contributor to morbidity and mortality in individuals with non-small cell lung cancer. Key features of CAC include alterations in body composition and body weight. Here, we explore the association between body composition and body weight with survival and ...

Subject

Cancer cachexia

Cachexia

Lung cancer

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