Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Abbosh, Christopher; M. Frankell, Alexander; Harrison, Thomas; Kisistók, Judit; T. Garnett, Aaron; Johnson, Laura; Veeriah, Selvaraju; Moreau, Mike; Chesh, Adrian; L. Chaunzwa, Tafadzwa; Weiss, Jakob; R. Schroeder, Morgan; Ward, Sophia; Grigoriadis, Kristiana; Shahpurwalla, Aamir; Litchfield, Kevin; Puttick, Clare; Biswas, Dhruva; Karasaki, Takahiro; R. Black, James; Martínez‐Ruiz, Carlos; Al Bakir, Maise; Pich, Oriol; B.K. Watkins, Thomas; L. Lim, Emilia; Huebner, Ariana; A. Moore, David; Godin-Heymann, Nadia; L’Hernault, Anne; Bye, Hannah; Odell, Aaron; Kalavakur, Paula; Gomes, Fábio; J. Patel, Akshay; Manzano, Elizabeth; T. Hiley, Crispin; Carey, Nicolas; Riley, Joan; E. Cook, Daniel; Hodgson, Darren; Stetson, Daniel; Carl Barrett, J.; M. Kortlever, Roderik; I. Evan, Gérard; Hackshaw, Allan; Daber, Robert; Shaw, Jacqui; J.W.L. 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doi:10.1038/s41586-023-05776-4

Public

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

Published in Nature • Apr 13, 2023

Authors:

Christopher Abbosh

Alexander M. Frankell

Thomas Harrison

Abstract

Circulating tumour DNA (ctDNA) can be used to detect and profile residual tumour cells persisting after curative intent therapy1. The study of large patient cohorts incorporating longitudinal plasma sampling and extended follow-up is required to determine the role of ctDNA as a phylogenetic biomarke...

Subject

Lung cancer

Tracking (education)

Oncology

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