Pragmatic evaluation of events and benefits of lipid lowering in older adults (
                    <scp>PREVENTABLE</scp>
                    ): Trial design and rationale

Joseph, Jacob; M. Pajewski, Nicholas; J. Dolor, Rowena; Ann Sellers, Mary; H. Perdue, Letitia; R. Peeples, Sheronda; M. Henrie, Adam; Woolard, Nancy; Schuyler Jones, W.; P. Benziger, Catherine; R. Orkaby, Ariela; S. Mixon, Amanda; J. VanWormer, Jeffrey; D. Shapiro, Michael; E. Kistler, Christine; S. Polonsky, Tamar; Chatterjee, Ranee; M. Chamberlain, Alanna; E. Forman, Daniel; U. Knowlton, Kirk; M. Gill, Thomas; Kristin Newby, L.; G. Hammill, Bradley; S. Cicek, Mine; A. Williams, Neely; E. Decker, Jake; Ou, Jiafu; Rubinstein, Jack; Choudhary, Gaurav; J. Gazmuri, Raúl; E. Schmader, Kenneth; L. Roumie, Christianne; P. Vaughan, Camille; B. Effron, Mark; M. Cooper‐DeHoff, Rhonda; A. Supiano, Mark; C. Shah, Raj; C. Whittle, Jeffrey; F. Hernandez, Adrian; T. Ambrosius, Walter; D. Williamson, Jeff; P. Alexander, Karen; Trial Research Group, PREVENTABLE

doi:10.1111/jgs.18312

Public

Pragmatic evaluation of events and benefits of lipid lowering in older adults ( PREVENTABLE ): Trial design and rationale

Shared by NobleBlocks on Apr 20, 2023 • 12:00 AM UTC

Authors:

Jacob Joseph

Nicholas M. Pajewski

Rowena J. Dolor

Abstract

Abstract Whether initiation of statins could increase survival free of dementia and disability in adults aged ≥75 years is unknown. PREVENTABLE, a double‐blind, placebo‐controlled randomized pragmatic clinical trial, will compare high‐intensity statin therapy (atorvastatin 40 mg) with placebo in 20,...

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