Levodopa Dose Equivalency in Parkinson's Disease: Updated Systematic Review and Proposals

T. Jost, Stefanie; Kaldenbach, Marie‐Ann; Antonini, Angelo; Martínez‐Martín, Pablo; Timmermann, Lars; Odin, Per; Katzenschlager, Regina; Borgohain, Rupam; Fasano, Alfonso; Stocchi, Fabrizio; Hattori, Nobutaka; Lingappa Kukkle, Prashanth; Rodríguez‐Violante, Mayela; Falup‐Pecurariu, Cristian; Schade, Sebastian; Niklas Petry‐Schmelzer, Jan; Metta, Vinod; Weintraub, Daniel; Deuschl, Günther; J. Espay, Alberto; Tan, Eng‐King; Bhidayasiri, Roongroj; S.C. Fung, Victor; Cardoso, Francisco; Trenkwalder, Claudia; Jenner, Peter; Ray Chaudhuri, К.; S. Dafsari, Haidar; International Parkinson and Movement Disorders Society Non‐Motor Parkinson Disease Study Group, the

doi:10.1002/mds.29410

Public

Levodopa Dose Equivalency in Parkinson's Disease: Updated Systematic Review and Proposals

Published in Movement Disorders • May 5, 2023

Authors:

Stefanie T. Jost

Marie‐Ann Kaldenbach

Angelo Antonini

Abstract

BACKGROUND: To compare drug regimens across clinical trials in Parkinson's disease (PD) conversion formulae between antiparkinsonian drugs have been developed. These are reported in relation to levodopa as the benchmark drug in PD pharmacotherapy as 'levodopa equivalent dose' (LED). Currently, the L...

Subject

Levodopa

Systematic review

Medicine

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