Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights

Koutros, Stella; A. Kiemeney, Lambertus; Pal Choudhury, Parichoy; L. Milne, Roger; López de Maturana, Evangelina; Ye, Yuanqing; Vijai, Joseph; Flórez-Vargas, Oscar; Dyrskjøt, Lars; D. Figueroa, Jonine; Dutta, Diptavo; G. Giles, Graham; A.T. Hildebrandt, Michelle; Offit, Kenneth; Kogevinas, Manolis; Weiderpass, Elisabete; L. McCullough, Marjorie; D. Freedman, Neal; Albanes, Demetrius; Kooperberg, Charles; K. Cortessis, Victoria; R. Karagas, Margaret; Johnson, Alison; Schwenn, Molly; Baris, Dalsu; Furberg, Helena; F. Bajorin, Dean; Cussenot, Olivier; Cancel‐Tassin, Géraldine; Benhamou, Simone; Kraft, Peter; Porru, Stefano; Carta, Angela; Timothy Bishop, D.; C. Southey, Melissa; Matullo, Giuseppe; Fletcher, Tony; Kumar, Rajiv; A. Taylor, Jack; Lamy, Philippe; Prip, Frederik; Kalisz, Mark; J. Weinstein, Stephanie; G. Hengstler, Jan; Selinski, Silvia; Harland, Mark; Teo, Mark; E. Kiltie, Anne; Tardón, Adonina; Serra, Cònsol; Carrato, Alfredo; García-Closas, Reina; Lloreta, Josep; R. Schned, Alan; H. Lenz, Petra; Ríboli, Elio; Brennan, Paul; Tjønneland, Anne; Otto, T.; Ю Овсянников, Д; Volkert, Frank; H. Vermeulen, Sita; K.H. Aben, Katja; E. Galesloot, Tessel; Turman, Constance; De Vivo, Immaculata; Giovannucci, Edward; J. Hunter, David; Hohensee, Chancellor; Hunt, Rebecca; V. Patel, Alpa; Huang, Wen‐Yi; Þorleifsson, Guðmar; Gago-Domínguez, Manuela; Amiano, Pilar; Golka, Klaus; C. Stern, Mariana; Yan, Wusheng; Liu, Jia; Alfred Li, Shengchao; Katta, Shilpa; Hutchinson, Amy; Hicks, Belynda; A. Wheeler, William; P. Purdue, Mark; A. McGlynn, Katherine; M. Kitahara, Cari; A. Haiman, Christopher; H. Greene, Mark; Rafnar, Þórunn; Chatterjee, Nilanjan; J. Chanock, Stephen; Wu, Xifeng; X. Real, Francisco; T. Silverman, Debra; García‐Closas, Montserrat; Stefánsson, Kāri; Prokunina‐Olsson, Ludmila; Malats, Núria; Rothman, Nathaniel

doi:10.1016/j.eururo.2023.04.020

Public

Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights

Published in European Urology • May 19, 2023

Authors:

Stella Koutros

Lambertus A. Kiemeney

Parichoy Pal Choudhury

Abstract

Our study identified multiple novel loci associated with bladder cancer susceptibility, bringing the number of independent markers at genome-wide significance to 24. Genetic susceptibility markers, coupled with lifestyle risk factors such as smoking, could guide future preventive measures and screen...

Subject

Bladder cancer

Genome-wide association study

Medicine

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