Early versus Later Anticoagulation for Stroke with Atrial Fibrillation

Fischer, Urs; Koga, Masatoshi; Strbian, Daniel; Branca, Mattia; Abend, Stefanie; Trelle, Sven; Paciaroni, Maurizio; Thomalla, Götz; Michel, Patrik; Nedeltchev, Krassen; H. Bonati, Leo; Ntaios, George; Gattringer, Thomas; Sandset, Else-Charlotte; J. Kelly, Peter; Lemmens, Robin; Sylaja, PN; Aguiar de Sousa, Diana; M. Bornstein, Natan; Gdovinová, Zuzana; Yoshimoto, Takeshi; Tiainen, Marjaana; Thomas, Helen; Krishnan, Manju; Shim, Gek; Gumbinger, Christoph; Vehoff, Jochen; Zhang, Liqun; Matsuzono, Kosuke; Saxhaug Kristoffersen, Espen; Desfontaines, Philippe; Vanacker, Peter; Alonso, Angelika; Yakushiji, Yusuke; Kulyk, Caterina; Hemelsoet, Dimitri; Poli, Sven; Paiva Nunes, Ana; Caracciolo, Nicoletta; Slade, Peter; Demeestere, Jelle; Salerno, Alexander; Kneihsl, Markus; Kahles, Timo; Giudici, Daria; Tanaka, Kanta; Räty, Silja; Hidalgo, Rea; J. Werring, David; Göldlin, Martina; Arnold, Marcel; Ferrari, Cecilia; Beyeler, Seraina; Fung, Christian; Weder, B.; Tatlisumak, Turgut; Fenzl, Sabine; Rezny‐Kasprzak, Beata; Hakim, Arsany; Salanti, Georgia; L. Bassetti, Claudio; Gralla, Jan; Seiffge, David; Horvath, Thomas; Dawson, Jesse

doi:10.1056/nejmoa2303048

Public

Early versus Later Anticoagulation for Stroke with Atrial Fibrillation

Published in New England Journal of Medicine • May 24, 2023

Authors:

Urs Fischer

Masatoshi Koga

Daniel Strbian

Abstract

BACKGROUND: The effect of early as compared with later initiation of direct oral anticoagulants (DOACs) in persons with atrial fibrillation who have had an acute ischemic stroke is unclear. METHODS: We performed an investigator-initiated, open-label trial at 103 sites in 15 countries. Participants w...

Subject

Medicine

Stroke (engine)

Atrial fibrillation

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