No Isolate, No Problem: Using a Novel Insertion Sequence PCR to Link Rats to Human Shigellosis Cases in an Underserved Urban Community.

G, Ritchie; V, Leung; CG, Himsworth; KA, Byers; LKF, Lee; SD, Chorlton; A, Stefanovic; MG, Romney; N, Matic; CF, Lowe

doi:10.1128/spectrum.04777-22

Public

No Isolate, No Problem: Using a Novel Insertion Sequence PCR to Link Rats to Human Shigellosis Cases in an Underserved Urban Community.

Shared by NobleBlocks on May 31, 2023 • 12:00 AM UTC

Authors:

Ritchie G

Leung V

Himsworth CG

Abstract

During an investigation into a cluster of Shigella flexneri serotype 2a cases in an underserved community, we assessed the relatedness of human and rat S. flexneri isolates utilizing a novel PCR targeting insertion sites (IS-PCR) of mobile elements in the Shigella genome characteristic of the cluste...

Subject

Rattus norvegicus

Shigella flexneri

Insertion Sequence

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