Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer

A. Wakelee, Heather; Liberman, Moïshe; Kato, Terufumi; Tsuboi, Masahiro; Lee, Se‐Hoon; Gao, Shugeng; Chen, Ke‐Neng; Dooms, Christophe; Majem, Margarita; Eigendorff, E.; Lucas Martinengo, Gastón; Bylicki, Olivier; Rodríguez‐Abreu, Delvys; E. Chaft, Jamie; Novello, Silvia; Yang, Jing; M. Keller, Steven; Samkari, Ayman; Spicer, Jonathan

doi:10.1056/nejmoa2302983

Public

Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer

Published in New England Journal of Medicine • Jun 3, 2023

Authors:

Heather A. Wakelee

Moïshe Liberman

Terufumi Kato

Abstract

BACKGROUND: Among patients with resectable early-stage non-small-cell lung cancer (NSCLC), a perioperative approach that includes both neoadjuvant and adjuvant immune checkpoint inhibition may provide benefit beyond either approach alone. METHODS: We conducted a randomized, double-blind, phase 3 tri...

Subject

Pembrolizumab

Medicine

Perioperative

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