Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study

Takata, Saori; Morikawa, Kei; Tanaka, Hisashi; Itani, Hidetoshi; Ishihara, Masashi; Horiuchi, Kazuya; Kato, Yasuhiro; Ikemura, Shinnosuke; Nakagawa, Hideyuki; Nakahara, Yoshiro; Seki, Yoshitaka; Bessho, Akihiro; Takahashi, Nobumasa; Hayashi, Kentaro; Endo, Takeo; Takeyama, Kiyoshi; Maekura, Toshiya; Takigawa, Nagio; Kawase, Akikazu; Endoh, Makoto; Nemoto, Kenji; Kishi, Kazuma; Soejima, Kenzo; Okuma, Yusuke; Yoshimura, Kenichi; Saigusa, Daisuke; Kanai, Yae; Ueda, Koji; Togashi, Akira; Matsutani, Noriyuki; Seki, Nobuhiko

doi:10.1177/17588359231177021

Public

Prospective exosome-focused translational research for afatinib (EXTRA) study of patients with nonsmall cell lung cancer harboring EGFR mutation: an observational clinical study

Published in Therapeutic Advances in Medical Oncology • Jan 1, 2023

Authors:

Saori Takata

Kei Morikawa

Hisashi Tanaka

Abstract

Background: The exosome-focused translational research for afatinib (EXTRA) study is the first trial to identify novel predictive biomarkers for longer treatment efficacy of afatinib in patients with epidermal growth factor receptor ( EGFR) mutation-positive nonsmall cell lung cancer (NSCLC) via a c...

Subject

Afatinib

Medicine

Internal medicine

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